Advanced Genetic Testing

 

 

The identification of chromosome abnormalities is done with a molecular biology approach for a faster diagnosis and answer to patients.

 

 

MLPA KIT


MLPA (Multiplex Ligation-dependent Probe Amplification) is a multiplex PCR method detecting abnormal copy numbers of up to 50 different genomic DNA or RNA sequences, which is able to distinguish sequences differing in only one nucleotide.

KIT QF-PCR


The QF-PCR (Quantitative Fluorescence PCR) uses fluorescent labelled primers of STR markers that are analyzed after fragment length separation in capillary gel electrophoresis.

 

 

KIT FOR BRCA 1 AND 2 SCREENING THROUGH SANGER SEQUENCING

 

BRCA1 and BRCA2 are tumor suppressor genes and they are composed of 23 and 27 exons respectively. The mutations observed are not localized in hotspots, but are distributed throughout the coding sequence. The kit B-Pure EasySeq has been developed to facilitate the analysis of sequencing for BRCA 1 and 2 mutations detection.

 

ONCOLOGY DIAGNOSTIC TESTS


SensiScreen® CE IVD are real-time PCR based assays for somatic mutation detection in cancer patients. SensiScreen® assays combine ultra high sensitivity with multiplexing capabilities, speed, ease-of-use and little hands-on-time. Important features of SensiScreen® assays are the implementation of PentaBase’s proprietary DNA analogue platform technology and the inclusion of baseblockers that make SensiScreen® assays superior to most current somatic mutation tests with regard to sensitivity and specificity.